Wednesday, June 6, 2007

Genetic Test Do Not Detect All Bosom Cancer Mutations

Genetic Test Do Not Detect All Bosom Cancer Mutations

Genetic test doesn't detect all gene mutations which caused by things related to cancer at

woman, what has history of health of big family mengidap bosom cancer or womb, said result

research now to be loaded in bevy journal of United States medical doctor, AMA, edition of this week.

" Woman having history of health of its(the family mengidap bosom cancer experiences test to know

do they have a number of bosom cancer mutations 1 ( BRCA 1) or bosom cancer 2 ( BRCA2) and partly

big between the women result of its(the test showing negativity," said Dr. Mary Clarke King in presentation

scientific in front of mass media, in parallel with publishing of this journal takes woman health theme.

King tells that in case BRCA1 since finds of mutation first time, there are some gene mutation which

in principle cannot be detected by conventional test method, although the test is done with as perfect

possibly."

In ACE most all genetic tests of BRCA1 and BRCA2 done by one health service activities companies. Almost

most of gene mutation that is successfully detected in commercial genetic test is disappearing it

a number of genes or the happening of gene duplication.

King from Universitas Washington in Seattle with its(the friends trying to find answer would

possibility that every existence of mutation overcome or got away from observation.

" That thing of vital importance, because risk problem is including action of surgical operation of lifting of womb cancer, actually

in a particular condition admits of prevented, and bosom cancer, where a patient will not ready experiences

dissected action aside from if no more of other alternative, means faces risk which really height,"

said King.

The research entangles 300 patients mengidap gracious cancer and bosom and at least three member

other family following test test laboratories and klinis but expressed result of of negativity . The researchers

applies verification of amplification and based on DNA method and RNA to detect existence of change

formation of gene ( genetic mutation) at BRCA1 and BRCA2.

They find that 35 or 12% from group of the woman patient experiences gene mutation BRCA1

or BRCA2 which because of disappearing it certain genes or the happening of gene duplication in number far

bigger than invention of change of gene in konvensial.

Meanwhile counted counted 5% experiences gene mutation having risk twofold is hit bosom cancer

but not threatened of womb cancer. One % woman is following in research of King and its(the friends having

gene mutation having risk 90% to be hit one of both types of the cancer having risk

hit a number of tumor types and that thing happened in them at the age of young.

But besides the mutation to to be found, the researchers also gets mutation with characteristic character

or individual valuable. There is again partly are between them experiencing gene mutation that is is unheard-of or not

its(the type.

" We try for always exposes x'self to development of research of continuation of gene mutation of bosom cancer

which will give explanation about genetic element factor at the the patients."

Meanwhile one of solution from the problem is increasing quality of test that is by the way of opening

wide opportunity to the side of market competes to develop gene test to determine BRCA1 and BRCA2

also other gene test.

" That thing is be including giving of patent for method or system gene test in non ekslusif because through emulation

free will be reached improvement quality of test systems tehnologi and by itself that thing will depress cost, because

purpose of we are give gene test far quicker and cheaper," said King.

Source: kapanlagicom

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